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Oral magnesium supplements combine magnesium with another substance such as a salt. Examples of magnesium supplements include magnesium oxide, magnesium sulfate, and magnesium carbonate. Elemental magnesium refers to the amount of magnesium in each compound. Figure 1 compares the amount of elemental magnesium in different types of magnesium supplements [28]. The amount of elemental magnesium in a compound and its bioavailability influence the effectiveness of the magnesium supplement. Bioavailability refers to the amount of magnesium in food, medications, and supplements that is absorbed in the intestines and ultimately available for biological activity in your cells and tissues. Enteric coating (the outer layer of a tablet or capsule that allows it to pass through the stomach and be dissolved in the small intestine) of a magnesium compound can decrease bioavailability [29]. In a study that compared four forms of magnesium preparations, results suggested lower bioavailability of magnesium oxide, with significantly higher and equal absorption and bioavailability of magnesium chloride and magnesium lactate [30]. This supports the belief that both the magnesium content of a dietary supplement and its bioavailability contribute to its ability to restore deficient levels of magnesium.
Thanks so much for the information.
My dd is asleep on the couch -- yes and missing school --because of the Klonopin. I keep saying the Trileptal has stopped working but that does not go over.
The deal for the week is to increase trileptal -- see if it works to control. If not, the neuro wants to add Topamax to her schedule. This drug's side effects are unacceptable to my husband and I -- and made that known to the neuro-- but he still wants to try it.
Thanks for letting me vent a bit!
As for magnesium, it comes in a variety of configurations. Each differs in terms of cost and how well it is absorbed. Magnesium oxide is the most common form on the market and it is about 60% absorbed by most people.
However, some absorb only 20%. Magnesium oxide is very cheap. If you develop diarrhea, you’ll know that the supplement is being poorly absorbed. The best-absorbed varieties include the malate, malate/citrate, citrate and gluconate forms. But the latter supplies too little magnesium; the one containing malate prevents aluminum absorption. I recommend either the malate or malate/citrate form.
Magnesium malate/citrate gives you 150 mg. of magnesium per capsule. Take two in the morning and two in the evening — and make sure it’s consumed with food. This powerful supplement also helps to induce sleep. Avoid the aspartate form since aspartate is an excitotoxin that inhibits melatonin release from the pineal gland.
What chelate form means:
"Magnesium Chelate (Amino Acid): A chemically reacted magnesium ion, bound to 1 or more amino acids, thus allowing the magnesium to enter through the intestinal wall via the amino acid pathway rather than active magnesium diffusion. A true reacted chelate differs from simply mixing the amino acids and minerals which is often referred to as "chelated"."